semisynthetic penicillin (trade names Principen and Polycillin and SK-Ampicillin)
An antibiotic that inhibits crosslinking of peptidoglycan chains in the cell wall of eubacteria. Cells growing in the presence of ampicillin synthesize weak cell walls, causing them to burst due to the high internal osmotic pressure. Amp resistance encoded by most transposons and plasmids is due to a periplasmic Beta-lactamase that breaks the Beta-lactam ring of ampicillin. Ampicillin is a derivative of penicillin.
Penicillin derivative with broad spectrum activity.
An antibiotic widely used in clinical treatment and rDNA research. It is a derivative of penicillin which kills bacteria by interfacing with the synthesis of the cell wall.
Has a broader spectrum of antimicrobial action than penicillin G, inhibiting the growth of Gram-positive and Gram-negative bacteria.
Ampicillin is a beta-lactam antibiotic that has been used extensively to treat bacterial infections since 1961. It can sometimes result in allergic reactions that range in severity from a rash (e.g. patients with mononucleosis) to potentially lethal anaphylaxis.
