Severe neurological damage associated with AIDS. Symptoms include memory loss, loss of motor control and behavioral abnormalities.
deterioration of intellectual faculties, often accompanied by emotional disturbance. HIV is active in the brain (central nervous system) and can cause dementia, even in those with high CD4 counts and low viral loads. Treatment usually involves an anti-HIV drug -- such as AZT -- that is able to cross the blood-brain barrier. (also called ADC)
The most common central nervous system (CNS) complication of HIV infection, ADC is characterized by a group of clinical presentations including loss of coordination, mood disorders, inability or difficulty in reasoning and loss of inhibitions. Usually occurs in latter stage disease but may occur sooner.