Single-voiced; having but one part; as, a monophonic composition; -- opposed to polyphonic.

Of or relating to a system for recording and reproducing sound, which has only one sound channel; also called monaural or mono. It contrasts with stereophonic (or stereo), quadraphonic, or surround-sound, which have two or more channels, and can thus reproduce the effect of the sound coming from more than one direction.

A musical instrument that is only capable of playing one note at a time. Music with only one voice part.

If a synth is monophonic, it can only play one note at a time. Contrast with polyphonic.