Definitions for "Genomic Imprinting" Add To Word List
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The phenomenon where there is a difference in the expression of the genes inherited from the father and the mother.
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An epigenetic modification in the expression of a gene or genes which varies in its effect depending on whether the active allele is inherited from the mother or the father.
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epigenetics, expression of imprinted genes is monoallelic and dependent upon the parents sex (parental imprinting), in contrast most genes (which are non-imprinted) have biallelic expression. This is an heritable change that does not alter DNA sequence. (More? Week 1 Notes)
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Inactivation by methylation of a gene on one of a pair of homologous chromosomes.
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Parent-specific expression or repression of genes or chromosomes in offspring.
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Differing expression of genetic material dependent on the sex of the transmitting parent.
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The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)
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See imprinting
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Epigenetic modifications of DNA or proteins surrounding DNA ( e.g. histones) that result in parent-specific expression or repression of genes in offspring.
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Instances of genetic transmission in which the expression of a gene is determined by whether the particular allelic form has been inherited from the mother or the father.
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An occurrence when the expression of a gene is affected by the parental origin.
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