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Related Topic"...Lymphocytes are either T-cells or B-cells..."
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T lymphocyte: immune cell that carries the "cluster of differentiation 8" (CD8) marker. CD8 T cells may be cytotoxic T lymphocytes or suppressor T cells. (See also cytotoxic T lymphocyte (CTL); T cell.)
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Another name for a "killer" T-cell.
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White blood cells are composed primarily of neutrophils, monocytes and lymphocytes. Lymphocytes are either T-cells or B-cells. T-cells (CD3 cells) are divided into T-helper (CD4 cells) and T-suppressor/cytotoxic (CD8 cells) cells.
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Related Topic" White blood cells are composed primarily of neutrophils, monocytes and lymphocytes..."
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Cluster of Differentiation Eight
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protein embedded in the surface of killer and suppressor T-lymphocytes. Blood tests that look for suppressor T-lymphocytes are actually looking for this protein.
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The cell surface protein CD8 is important for recognition by the T-cell receptor of antigenic peptides bound to MHC class I molecules. It acts as a co-receptor by binding to the lateral face of MHC class I molecules.
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a T-cell signalling/co-receptor molecule involved in MHC-I adhesion
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A protein embedded in the cell surface of T-suppresser cells.
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Related Topic"...T-cells (CD3 cells) are divided into T-helper (CD4 cells) and T-suppressor/ cytotoxic (CD8 cells) cells..."
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CD8 (cluster of differentiation 8) is a glycoprotein which serves as a co-receptor that is expressed on the surface of cytotoxic T cells. CD8 consists of an α and a ß chain, which both resemble an immunoglobulin-like domain that is connected to the membrane by a thin stalk. It is attracted to the α3 portion of the Class I MHC molecule.
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