A genetic change that is caused by substitution of a single nucleotide.
A common nucleotide variant in DNA at a single site.
A change in which a single base in the DNA differs from the usual base at that position.
A variation of a gene that differs by one base pair. An example would be substituting an “A” where there is usually a “C” in the genetic code.
Intraspecies variation at a given site in a nucleotide sequence.
Variation in the nucleotide allele at a certain nucleotide position in the human genome. When the change occurs it is called a polymorphism, and polymorphisms accumulate over time. A polymorphism can be very common (found in a significant fraction of global or localized populations) or very rare (found in a single individual). Common variations are used to track the evolution of the human genome over time (population genetics) and can be graphically represented in a haplogroup or phylogenetic tree.
A SNP (single nucleotide polymorphism) is a single chemical unit (base pair) variation in a stretch of DNA. Human DNA is estimated to vary only 1 in every 1000 base pairs between any two people.
A polymorphism where the alleles differ by the replacement of a single nucleotide in the DNA sequence. For most SNPs, only two of the four possible nucleotides (A, T, C, or G) are observed.
Inter-individual variations in the genetic code at the level of one nucleotide.
Individual differences at a single nucleotide of DNA. This genotypic difference can cause a phenotypic difference in hair colour, height or response to a drug, depending on the gene.
A DNA sequence variation that involves a change in a single nucleotide
A change in the DNA that happens when a single nucleotide (A, T, G, or C) in the genome sequence is altered. A person has many SNPs that together create a unique DNA pattern for that individual.
A variation in a gene caused by the change of a single base in DNA.
One base in a sequence is changed to a different base.
(SNP) DNA sequence variations that occur when a single nucleotide (A, T, C, or G) in the genome sequence is altered. See also: mutation, polymorphism, single-gene disorder
Scattered single-base pair variations within the genetic code of the individuals of a population. SNPs determine ways that subpopulations within a species differ and provide information about variations of protein expression and structure of interest to p
(SNP) Common, but minute, variations that occur in human DNA at a frequency of one every 1,000 bases. These variations can be used to track inheritance in families.
A change in a single "letter" of DNA "text", such as replacing a C with an A in one location. However, not every random change is categorized as SNP but only those which, compared to the average human genome, appear with a frequency of at least 1% in the population. Every individual carries numerous SNPs, some of which can result in disease. Target validation Basic step in drug development; test of the specific effect of a drug candidate on a target biomolecule, with the intention to create a therapeutic effect.
A common single-base pair variation in a DNA sequence.
The most common genetic differences among individuals resulting from minute, single-base changes in the genetic code.
single-base variations in the genetic code between different individuals of the same species.
Single nucleotide variations in the genome sequence.
Single base pair variations or mutations between the DNA of a population. SNPâ€(tm)s can be scattered randomly throughout an organismâ€(tm)s DNA.
The most common type of DNA sequence variation. An SNP is a change in a single base pair at a particular position along the DNA strand. When an SNP occurs, the gene's function may change, as seen in the development of bacterial resistance to antibiotics or of cancer in humans.
Variability among individuals of the DNA sequence at one specific base within a gene. Particular SNP sites within the coding regions of proteins are chosen for investigation because nucleotide changes (i.e. mutations) at these sites could lead to amino acid substitutions that will affect protein function. Each SNP is studied to determine if it is associated with a genetic disease.
A Single Nucleotide Polymorphism or SNP (pronounced snip) is a DNA sequence variation occurring when a single nucleotide - A, T, C, or G - in the genome (or other shared sequence) differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. In this case we say that there are two alleles : C and T.