A group of alleles of different genes that are linked closely enough to be inherited as a unit.
The specific allelic constitution of a chromosome. Often, the allelic com- position of one or a few linked genes under investigation.
A set of genetic determinants located on a single chromosome.
The genetic makeup of a single chromosome.
This is the tissue type contributed by either the mother or father to their offspring. It is implied that it represents the genes on one set of parental chromosomes. When a transplant procedure is between a donor and recipient who are haplotype identical, it means that the tissue type or HLA type of each is identical in respect to mother or father but not identical to the other. In some situations, if the discrepancy is not too great the transplant may still be possible if the underlying disease makes the risk of partial compatibility warranted. Conditioning of the recipient and lymphocyte depletion of the donor stem cell suspension are steps taken to mitigate the risk of immune cell activation by the tissue type differences.
A set of genes on a single chromosome.
Genotype of genetically linked loci that are inherited in a block as a single unit. Your Y-DNA haplotype is a set numbers, each number representing your allele at a given STR marker. Two or more haplotypes may be compared as a check for a genetic relationship.
a set of genes that determine different antigens but are closely enough linked to be inherited as a unit; also : the antigenic phenotype determined by a haplotype.
Set of allelic states found at neighbouring loci in a chromosome, as inherited from a parent. Haplotypes can be broken down by recombination. A haplotype shared among unrelated individuals affected with a genetic disease may indicate that a gene causing the disease maps to that genomic region.
Refers to "half of a genotype". It is the set of alleles on a single chromosome, or on all the single chromosomes passed from a parent to an offspring, or on a localized region of a single chromosome.
the results of the Y DNA test, the markers and their scores [allele values], are called a haplotype. When two or more results are a close match, the haplotype indicates sharing of a common ancestor. The haplotype, is also sometimes referred to as a fingerprint, blueprint, signature, pattern. The numbers are also known as "allele values" and sometimes are referred to as STR numbers.
An alternative form of a group of genes, part of a chromosome or a gene complex. The term is applied to groups of genetic loci, whereas the term 'allele' refers to alternative forms of a single gene.
The particular combination of alleles in a linked group encoded by genes in close vicinity on the same chromosome.
the set of alleles which are carried on one of a pair of homologous chromosomes.
a set of allele values of many markers measured for one individual and identified as coming just from one parent, particularly markers on the chromosome.
Combinations of two or more gene variants; can be within the same gene, within same group of genes on one chromosome or on different chromosomes.
Broadly, the complete set of results obtained from multiple markers located on a single chromosome. For the Y chromosome, the term is restricted by convention to allele values (number of repeats) obtained from microsatellite (STR) markers, as described by the Y Chromosome Consortium (YCC).
a block of DNA containing gene variations that researchers believe are passed as a unit to successive generations
a chromosome segment all the chromosomes inherited from one parent
a chunk of DNA that contains gene variations linked so closely that researchers believe they were inherited as a unit
a combination of alleles at adjacent marker locations, co-inherited from generation to generation
a combination of genotypes on the same chromosome that tend to be inherited as a group
a combination of variations in a gene
a group of genetic rarities that sit on the same chromosome and tend to be inherited together, passed from parent to child as a chunk
a linked set of genes associated with one haploid genome
a multisite haploid genotype at two or more polymorphic sites on the same chromosome in a defined DNA region
a set of alleles found at linked polymorphic sites (such as within a gene) on a single (paternal or maternal) chromosome
a set of closely linked alleles, which are genes or variations in the sequence of genetic information on a segment of DNA
a set of closely linked genes that tends to be inherited together as a unit
a set of closely linked genetic markers present on one chromosome, which tend to be inherited together
a set of genetic mutations
a set of nucleotide sites gathered from a stretch of DNA
a specific combination of alleles (genetic variations) found on a single chromosome, a sort of genetic signature
a specific sequence of genetic variation that lies on the same chromosome
a specific sequence of nucleotides on a single chromosome
a stretch of DNA where the SNPs are correlated with each other, and that is a project that's now underway and is going to have in the next roughly two years the ability to produce this gold standard set of SNPs
A set of several different DNA or gene variants present together in a particular section of a chromosome.
A set of closely related polymorphisms that are inherited as a unit. A haplotype can be considered a DNA signature of a paternal lineage. Haplotypes are often used to compare different populations.
Different combinations of polymorphisms are known as haplotypes.A set of closely linked alleles (genes or DNA polymorphisms) inherited as a unit.A contraction of the phrase "haploid genotype."
A set of signature genetic changes (polymorphisms) that are normally grouped closely together on the DNA strand. This set of changes is usually inherited as a group and is referred to as a haplotype (Ford, 1997).
Pertaining to a particular set of alleles at linked loci (or nucleotide changes within a gene) that are found together on a single homolog. In linkage studies with backcross offspring and RI strains, the haplotypes associated with each sample provide a means for determining the order of loci (see Chapter 9). See Haplotype in the MGI Glossary.
The alleles found on a single chromosome present at the known polymorphic sites in a gene or region of genomic DNA. The two haplotypes of a gene carried by an individual are that individual's alleles for the gene. HAP(tm) Marker A derivation of the technical term haplotype, which at the molecular level, is a combination of nucleotides that are present at each of the polymorphic sites on a chromosome in selected regions of a gene. These selected regions include the region immediately upstream of the first coding exon (the promoter); the protein coding regions (exons); the intron/exon boundaries; and the last exon through at least the termination codon. A HAP(tm) Marker is discovered electronically using proprietary algorithms based on well-established genetic principles. HAP(tm) Technology The combination of our HAP® Database, our DecoGen Informatics System, our HAP(tm) Typing Facility and our clinical genetics expertise. HAP(tm) Typing HAP(tm) Typing describes the process of determining which HAP(tm) Marker is present for each of the two versions of a gene in a patient's clinical sample.
1. A group of alleles, each from a different locus in the same region of a chromosome, that exist in the same double helix.
The collective genotype of a number of closely linked loci; the constellation of alleles present at a particular region of genomic or mitochondrial DNA.
A set of Y chromosome DNA results or mitochondrial DNA results.
The particular combination of alleles present within a defined region of some chromosome. Originally was coined to describe MHC antigens, but now is used to describe RFLP patterns and certain other situations.
a group of nearby alleles that are inherited together
A specific set of alleles located on the same chromosome
A collection of alleles that are usually inherited together.
One person's set of values for the markers that have been tested. Two individuals that match exactly on all markers have the same haplotype.
The set of genes, comprised of one allele of each gene, that make the genotype.
A way of denoting the collective genotype of a number of closely linked loci on a chromosome.
A specific combination of linked alleles in a cluster of related genes.
Closely linked alleles on a single chromosome that are usually inherited as a group and determine a particular phenotype.
Particular combinations of alleles/markers observed. Common haplotype present in population at frequency 5
the linear, ordered arrange-ment of alleles on a chromosome. Haplotype analysis is useful in identifying recombination events. [Source: NHBLI/NCBI Glossary
A specific combination of alleles or sequence variations that are likely to be inherited together.
The combination of alleles of different genes that are present in an individual.
A specific combination of single nucleotide polymorphisms (SNPs) associated with a particular gene used to measure genetic variability. Haplotypes are a convenient way to organise genetic variation and particular haplotypes can be correlated with drug response.
The specific combination of alleles in a defined region of a chromosome.
Unique DNA sequence used to distinguish differences among individuals and populations.
A particular combination of closely linked genes on a chromosome inherited from one patient.
One of the alternative forms of the genotype of a set of genes that are inherited as a unit. This term is applied to gene complexes rather than the term allele, which refers to one of the forms of a single gene.
Closely linked alleles along a region of a chromosome which tend to be inherited together. A haplotype is identified by patterns of SNPs. Haplotype maps are intended to identify complex genetic variations of importance to health and disease.
A set of closely linked alleles (genes or DNA polymorphisms) inherited as a unit. The line of data in the charts of this website for each participant constitutes the haplotype for that person. Haplotypes can be grouped together to suggest a common distant ancestor.
The genetic makeup of an individual with respect to a specific pair of alleles or genes.
Conventionally used to refer to the particular alleles present at the four genes of the HLA complex on chromosome 6. The term is also used to describe DNA sequence variants on a particular chromosome adjacent to or closely flanking a locus of interest.
The term for the set of numbers that consists of your Y-chromosome or mitochondrial DNA results. Haplotypes are also known as signatures.
A haplotype is the genetic constitution of an individual chromosome. Haplotype may refer to only one locus or to an entire genome. In the case of diploid organisms such as humans, a genome-wide haplotype comprises one member of the pair of alleles for each locus (that is, half of a diploid genome).