a sequence of bases at a unique physical location in the genome, which varies sufficiently between individuals that its pattern of inheritance can be tracked through families and/or it can be used to distinguish among cell types. A marker may or may not be part of a gene. Markers are essential for use in linkage studies and genetic maps to help scientists to narrow down the possible location of new genes, and to discover the associations between genetic mutations and disease.
gene with a known location on a chromosome; used as a point of reference when doing linkage analysis
Identifiable physical location on a chromosome, the inheritance of which can be monitored.
Marker can refer to a gene with a known location on a chromosome and a clear-cut phenotype, that can be used as a point of reference when mapping a new mutant or antigenic markers that serve to distinguish cell types
In genome mapping, any feature (such as a known DNA sequence) whose location in the genome can be determined.
Also called a Locus (pl. loci). A gene of a known location on a chromosome. See STR marker. FTDNA Y-DNA tests use 12, 25, or 37 STR markers.
An identifiable DNA sequence that is inherited in Mendelian fashion, and which facilitates the study of inheritance of a trait or a linked gene.
Any neutral polymorphism used in linkage or association analysis.
A genetic trait of which one allelic form is selected or screened for following recombination.
A segment of DNA, often a microsatellite, used for parentage verification purposes or as an indicator of the presence of a gene allele known to be close by on the chromosome.
a distinctive sub-unit of DNA, often not part of a gene. Often used interchangeably with locus, but referring to the contents of the site, rather than the site itself.
An easily detected gene or chromosome region used for identification.
An identifiable physical location on a chromosome that is variable between individuals and whose inheritance can be monitored. A term commonly used along with allele values in describing an individual's haplotype. Marker labels, such as M173 or DYS388, have no intrinsic meaning.
a definable segment of DNA
a location on the Y chromosome that may be tested for Genetic Genealogy
an experimental procedure to determine the alleles at a locus
an identifiable and inheritable difference that can be mapped to a location on a chromosome
an identifiable region of variable DNA
a phenotypic characteristic (e
a piece of DNA that lies near a gene and is usually inherited with it
a piece of the DNA molecule that is associated with a certain trait of an organism
a section of DNA that can track with a disease
a small piece of the DNA that can be identified and characterized
a specific motif - or pattern - of the nucleotides Adenine, Thymine, Cytosine, Guanine which are the basic components of DNA
a very smart choice for DNA quantitation within your gel
a visible or otherwise detectable tag that is used to track or monitor genetic differences/changes in a target organism, population, etc
A gene which, on expression, allows easy identification of cells which carry it. Normally used to describe genes carried by a vector which are used to detect vector presence or state in a host cell.
A segment of DNA with an identifiable physical location on a chromosome whose inheritance can be followed. (taken from www.genome.gov)
A gener of DNA fragment with a known location on a chromosome that is associated with a certain disease
gene or DNA sequence with a known physical location on a chromosome and is associated with a certain trait or characteristic. It can be used as a point of reference when looking for other genes.
A genetic flag or trait used to verify successful transformation, and to indirectly measure expression of inserted genes. For example, a gene used as a marker in BT11 confers tolerance to the herbicide Liberty[TM].
A character or gene which, by virtue of linkage, can be used to indicate the presence of another gene.
A reference to a specific location on a DNA molecule. Also called a locus
A component of a genetic map which uniquely identifies a locus.
DNA sequence whose chromosomal location has been determined and which can be used in linkage analyses to track the inheritance patterns of genes that have not yet been identified, but whose approximate locations are known; markers typically have multiple alleles.
Biochemical or DNA polymorphism occurring close to a gene and used in gene tracking.
A piece of DNA that lies on a chromosome so close to a gene that the marker and the gene are inherited together. A marker is thus an identifiable heritable spot on a chromosome. A marker can be an expressed region of DNA (a gene) or a segment of DNA with no known coding function. All that matters is that the marker can be detected and trailed. See the entire definition of Marker
A gene or other segment of DNA whose position on a chromosome is known and whose inheritance can be monitored.
A detectable genetic variant, such as one of the ABO blood types. Some closely linked markers can be used to deduce the presence or absence of deleterious genes.
A physical location (locus) on the chromosome. Family Tree DNA offers 3 levels of Y-DNA testing: 12-marker, 25-marker and 37-marker.
A particular sequence of DNA (for which the location is known), that can be used as an established “landmark” within the genome to tell where and on which chromosome a gene may be located.
A section of DNA that is polymorphic (see polymorphism), which can be used to identify whether or not nearby linked genes are present.
A chromosome, usually small, of unknown origin and unidentifiable from its G-banding pattern.
Also known as a genetic marker, a segment of DNA with an identifiable physical location on a chromosome whose inheritance can be followed. A marker can be a gene, or it can be some section of DNA with no known function. Because DNA segments that lie near each other on a chromosome tend to be inherited together, markers are often used as indirect ways of tracking the inheritance pattern of genes that have not yet been identified, but whose approximate locations are known.
Any genetically derived phenotypic difference used in the analysis of inheritance patterns or to differentiate between types of cells. An observable site on a chromosome that is heritable and can be either a genetically-expressed region or noncoding segment of DNA (intron).
An identifiable segment of DNA (e.g., RFLP, VNTR, microsatellite) with enough variation between individuals that its inheritance and co-inheritance with alleles of a given gene can be traced; used in linkage analysis
a piece of DNA that lies on the chromosome so close to a gene that the two are inherited together. Like a signpost, markers are used during genetic testing and research to locate the nearby presence of a gene. See chromosome, deoxyribonucleic acid (DNA).
a gene or DNA fragment with a known location on a chromosome that is associated with a certain disease; it can be used as a point of reference when looking for disease-causing mutations
Loci used as a study indicator
See " Gene Marker"
The current human genetic map has about 1000 markers, or 1 marker spaced every 3 million bp. (IOOakRidge) Marcador Um mapa genômico descreve a ordem dos genes ou de outros marcadores e o espaçamento entre eles, em cada cromossomo. (POPrGenoma)
See genetic markers.
An identifiable physical location on a chromosome (e.g., restriction enzyme cutting site, gene) whose inheritance can be monitored. Markers can be either expressed regions of DNA (genes), or some segment of DNA with no known coding function but whose pattern of inheritance can be determined.
A gene with a known location on a chromosome and a clear-cut phenotype (physical appearance or observable properties) that is used as a point of reference when mapping another locus (physical position on a chromosome).
a distinguishing feature that can be used to identify a particular gene location on a chromosome.
Any genetic element ( locus, allele, DNA sequence or chromosome feature) which can be readily detected by phenotype, cytological or molecular techniques, and used to follow a chromosome or chromosomal segment during genetic analysis. See centromere marker; chromosome marker; DNA marker; genetic marker; inside marker; outside marker.
A physical location on a chromosome which can be reliably monitored during replication and inheritance. Markers on the Human Transcript Map are all STSs.
a feature in the DNA that helps to specify a specific location on a chromosome. A marker may be a gene or it may be a unique area of DNA outside of a gene. Genetic markers are useful mapping the location of genes and for doing linkage. The markers themselves are not always the genetic feature that is causing the disease in a family, but looking for patterns of markers in the family can help determine the location of the disease causing gene
A gene or DNA sequence having a known location on a chromosome. On the tables presented here, each column represents a marker.
gene of known location on a chromosome and phenotype that is used as a point of reference in the mapping of other loci.
A variable segment of DNA, often located near a gene. An allele at the marker is typically inherited along with the corresponding allele at the nearby disease gene.