Destitute or deprived of inhabitants; deserted; uninhabited; hence, gloomy; as, a desolate isle; a desolate wilderness; a desolate house.

Laid waste; in a ruinous condition; neglected; destroyed; as, desolate altars.

Destitute of; lacking in.

To lay waste; to ruin; to ravage; as, a fire desolates a city.

leave someone who needs or counts on you; leave in the lurch; "The mother deserted her children"

reduce in population; "The epidemic depopulated the countryside"

devastate or ravage; "The enemy lay waste to the countryside after the invasion"

made uninhabitable; "upon this blasted heath"- Shakespeare; "a wasted landscape"

(1) deserted or uninhabited, as in: They washed up on the shore of a desolate island. (2) miserable, as in: I am desolate that you believed I could do a thing like that.