a common predisposing factor

a critical factor in whether or not IgA-deficient persons have illness (frequent infections, autoimmune disorders, atopy, malabsorption)

an ideal disease for development of gene therapy methods, because there is selective pressure on nontransduced T cells, because they are not viable

a risk factor for bacterial overgrowth, a further predisposing condition is necessary for development of this disorder but was not present in this case

a risk factor for developing the degenerative diseases of aging according to the preponderance of evidence existing in the scientific literature