Barnacle Bill (released in the U.S. as All at Sea) is a 1957 comedy, starring Alec Guinness, playing an unsuccessful navy man as well as six of his maritime ancestors.

Barnacle Bill is a 1930 Fleischer Studios animated short film. It was part of the Talkartoons series, and featured Betty Boop (here known as Nancy Lee) and Bimbo.

Barnacle Bill is a 40 centimeter rock on Mars in Ares Vallis. It was the first rock on Mars analyzed by the Sojourner rover using its Alpha Proton X-ray Spectrometer. The encounter occurred during Sol 3 of the Mars Pathfinder mission on the surface of Mars and took ten hours to complete.

Barnacle Bill, aka Bollock chops Yezzybill the Sailor, is a traditional bawdy folk song which, according to Cray (1992), was originally titled Abram (or Abraham) Brown. There are several versions of the bawdy song in the Gordon "Inferno" Collection at the Library of Congress folklife archive. The first printed version of the song is in the public domain book Immortalia.

Barnacle Bill is a 1941 film starring Wallace Beery and Marjorie Main. The screen comedy was directed by Richard Thorpe.