"It Takes Two" was a 1966 hit single recorded by Marvin Gaye and Kim Weston for Motown's Tamla label.

It Takes Two was a game show where contestants gave numerical answers to questions (which are usually crazy stunts and/or demonstrations) in order to win.

It Takes Two was a 1995 film starring Mary-Kate and Ashley Olsen. The movie title was taken from the song "It Takes Two", sung by Marvin Gaye and Kim Weston. The song was featured prominently in the movie.

It Takes Two is the Australian version of UK series Just the Two of Us http://www.ebroadcast.com.au/enews/It_Takes_Two_-_Judges_Announced_220506.html. The show, which premiered on Sunday, May 28 2006 at 6.30pm, featured a number of celebrities (or stars) who were paired with a singing coach/professional singer. Each week, each team sang a duet and competed against other pairs in a competition to impress a panel of judges and the viewing public in order to survive potential elimination.

"It Takes Two" is the 48th episode of the ABC television series, Desperate Housewives. It was also the second episode of the show's third season. The episode was written by Kevin Murphy and Jenna Bans and directed by David Grossman.

It Takes Two (Nan xiong nan di) is a 1982 Hong Kong film directed by Karl Maka.