USS Sampson (DDG-10), named for Admiral William T. Sampson USN (1840–1902), was a Charles F. Adams-class guided missile destroyer in the United States Navy.

USS Sampson (DDG-102) will be an Arleigh Burke-class destroyer in the United States Navy. She was authorized in 2002 and will honor Admiral William T. Sampson.

Four ships in the United States Navy have been named USS Sampson for Rear Admiral William T. Sampson.

USS Sampson (DD-63) was the lead ship of her class of destroyers of the United States Navy. She was the first Navy ship named for Admiral William T. Sampson (1840–1902).

The second USS Sampson (DD-394) was a Somers-class destroyer in the United States Navy. She was named for William Thomas Sampson.