a genotoxic drug, a chemotherapy agent that affects DNA and alters its function

a chemotherapy used in combination in bone sarcoma treatment.

VP16, derivative of podophyllotoxin that interferes with nucleoside transport into cells and action of topoisomerase II.

Chemotherapy drug used in treatment of testicular cancer, small-cell lung cancers and others.

A semisynthetic derivative of podophyllotoxin, etoposide can be administered orally or intravenously. It is often used for neoplastic disease. Chemically, etoposide is 4'-demethylepipodophyllotoxin 9-[4,6-0-(R)-ethylidene-(beta)-D-glucopyranoside] and has molecular formula: C 29 H 32 O 13 . Possible side effects include: low blood counts, nerve numbness, shortness of breath, hair loss, nausea, vomiting, mouth sores, and diarrhea.

A type of chemotherapy that inhibits cancer cell growth.

An anticancer drug that belongs to the families of drugs called podophyllotoxin derivatives and topoisomerase inhibitors.

An anticancer drug that is a podophyllotoxin derivative and belongs to the family of drugs called mitotic inhibitors.

Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. It is used as a form of chemotherapy for malignancies such as lung cancer, testicular cancer, lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. It is often given in combination with other drugs.