a large glycoprotein molecule, secreted by follicle cells of the thyroid gland, in which iodine and tyrosine are combined to form thyroid hormones
A circulating transport globulin that binds thyroid hormones.
A protein in the thyroid in which thyroid hormones are manufactured and stored. Some thyroglobulin is secreted into the blood stream and can be used as a marker for the presence of thyroid disease, especially cancer.
A large, dimeric protein synthesized by thyroid epithelial cells. Serves as a precursor for synthesis of thyroid hormones.
an iodine containing protein that is obtained from the thyroid gland and exhibits the general properties of the globulins
A large protein that acts as a storage site for thyroid hormones within the thyroid gland. Following surgical removal of a cancerous thyroid gland, the level of Tg in the bloodstream can be monitored to detect thyroid cancer recurrence.
A protein found in thyroid follicular cells that catalyzes the production of T3 and T4 from MIT and DIT.
(THIGH-roe-GLOB-yu-lin) The form that thyroid hormone takes when stored in the cells of the thyroid. If the thyroid has been removed, thyroglobulin should not show up on a blood test. Doctors measure thyroglobulin level in blood to detect thyroid cancer cells that remain in the body after treatment.
A protein in the thyroid gland, a small amount of which gets into the blood. Its level is followed after thyroid surgery to detect recurrence of thyroid cancer.
A protein in the thyroid that combines with iodine to produce thyroid hormone.
An iodine-containing glycoprotein occurring in the colloid of the follicles of the thyroid. Thyroglobulin combines with iodine to form the iodothyronines, thyroxine (T4) and triiodothyronine (T3). hyrotoxicosis Hyperthyroidism
Iodinated glycoprotein in thyroid follicles that binds thyroid hormone; precursor of T3 and T4.
Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Tg is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). The active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase which has been referred to as Tetraiodothyronine 5 deiodinase.