A transmembrane protein on the surface of T cells that recognizes antigens associated with MHC proteins on the surface of phagocytes.
A cell surface molecule that binds a T cell. 797
A protein found on the surface of T cells. Alpha-beta TCR binds to bits of foreign peptides (or sometimes body peptides, like myelin) attached to cell surface 'display' proteins on antigen presenting cells.
The clonally distributed antigen receptor on CD4 and CD8 T lymphocytes that recognizes complexes of foreign peptides bound to self MHC molecules on the surface of APCs. The most common form of TCR is composed of a heterodimer of disulfide-linked transmembrane polypeptide chains, designated a and ß, each containing one terminal Ig -like variable (v) domain, one Ig-like constant (c) domain , a hydrophobic transmembrane region, and a short cytoplasmatic region. (Another less common type of TCR , composed of ? and d chains, is found on a small subset of T cells and recognizes different forms of antigens )
An antigen-binding protein that is located on the surfaces of killer T cells and mediates the cellular immune response of mammals. The genes that encode T cell antigens are assembled from gene segments by somatic recombination processes that occur during T lymphocyte differentiation.
Cell surface molecule on T cells which recognizes and binds to MHC-antigen complex on body cells and antigen-presenting cells
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of chemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.