An inhibitor of bacterial folic acid synthesis, which has been highly effective against pneumococcal, staphylococcal, streptococcal, E. coli, and Klebsiella pneumoniae infections, and also useful in acute gonococcal arthritis.
Sulfadiazine is a sulfonamide antibiotic. It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).