A change or mistake in a gene which is found in the cells of the body but not in the germ or sex cells. Somatic mutations cannot therefore be passed on to future generations.
A process occurring during B-cell maturation and affecting the antibody gene region, which permits refinement of antibody specificity.
The alteration of a gene in the cells of a specific tissue causes the gene to become a cancer-causing gene or oncogene. It is called "somatic" to distinguish it from germ cell mutation which, can be passed from parent to offspring. Most cases of leukemia are caused by a somatic mutation in a primitive marrow (blood-forming) cell.
a mutation that occurs in the somatic (i
A mutation in the DNA of any cell in the body (somatic cells), except those in the germline.
mutation that occurs in any cell of the body other than a germ-line cell, and thus is not heritable
mutation in cells of the body other than in oogenic or spermatogenic cells.
A non-heritable genetic change occurring within a somatic cell, also known as an acquired mutation.
Mutation in cells that make up the body rather than in germ cells. Somatic mutations usually lead to sporadic cancers.
A mutation occurring in a somatic cell, which is neither inherited nor passed to offspring.
a DNA change present in body cells other than the egg or sperm (germ cells).
A mutation occurring in any cell that is not destined to become a germ cell; if the mutant cell continues to divide, the individual will come to contain a patch of tissue of genotype different from the cells of the rest of the body.
Variation in somatic cell lines (some cancer association). Mechanism used for IgG variation
Mutation occurring in a somatic cell and therefore affecting only the descendants of that cell; it is not inherited.
Genetic changes arising in individual cells, not hereditary. A number of somatic mutations in different genes may be necessary for cancer to develop, a "multi-step" process. See also: Mutation. See also: Hereditary-Mutation
A mutation which occurs in a somatic cell. It will affect all cells descending from the mutant cell within the organism, but will not affect offspring. Cancer is usually the result of somatic mutation.
Mutations that occur during in-utero development
a change in DNA that starts in one cell of the body after an embryo is formed. All the cells that arise from it will have the same mutation, which in some cases can form cancer. This kind of mutation is different from any inherited mutations that are present at birth in all the cells of the body. Somatic mutations are not passed on to children. Compare with inherited mutation. See also mutation, deoxyribonucleic acid.