Definitions for "Paget's disease"
Lesion of the nipple that clinically resembles an eczematous rash, thought to be a manifestation of high nuclear grade, comedo DCIS affecting subareolar ducts and extending into the epidermis. An associated invasive breast carcinoma is seen in 35% to 50% of affected patients.
also known as osteitis deformans, a chronic skeletal disorder that can lead to deformed or enlarged bones. The bones excessively breakdown and reform leading to bones that are weak, possibly resulting in fractures, pain, and arthritis.
A disease of the bone that initially results in the excessive resorption of bone followed by the replacement of normal bone marrow with vascular and fibrous tissue.