an experimentally determined dose at which there was no statistically or biologically significant indication of the toxic effect of concern
That dose of chemical at which there are no statistically or biologically significant increases in frequency or severity of adverse effects seen between the exposed population and its appropriate control. Effects may be produced at this dose, but they are not considered to be adverse.
No Observed Adverse Effect Level. Compare? A level of exposure which does not cause observable harm.
No Observed Adverse Effect Level. The highest dose of a chemical in a study, or group of studies, that did not cause harmful health effects in people or animals.
No observed adverse effect level. Greatest concentration or amount of an agent, found by experiment or observation, that causes no detectable adverse alteration of morphology, functional capacity, growth, development or life span in an organism, system or (sub) population.
No Observable Adverse Effect Level. The No Observable Adverse Effect Level is used to calculate the risk for many toxic substances. For methylmercury, the NOAEL is calculated based on the most sensitive endpoint tested - the neurological development in children exposed in utero to methylmercury as a result of their mothers’ consumption of seafood containing methylmercury.
No observed adverse effect level. The dose of a chemical at which there were no statistically or biologically significant increases in frequency or severity of adverse effects seen between the exposed population and its appropriate control. Effects might be observed at this dose but were judged not to be "adverse."
bserved dverse ffect evel. The highest dose of a chemical in a study, or group of studies, that did not cause harmful health effects in people or animals.
No Observed Adverse Effect Level. The NOAEL is the highest dose from a study that did not find any adverse health effects. The NOAEL is often used to derive MRLs and RfDs.
no-observed-adverse-effects level
No observed adverse effect level. An exposure level at which there was no statistically or biologically significant increase in the frequency or severity of adverse effects between the exposed population and its appropriate control group.
No-Observed-Adverse-Effect Level; the highest dose in an experiment which did not produce an observable adverse effect.
Intake level of a dietary supplement at which there are no credibly-substantiated adverse reactions observed in humans. From CRN.
A level of intake of a supplement where no side effects have ever been known.
No Observed Adverse Effect Level. The highest tested dose of a substance that has been reported to have no harmful (adverse) health effects on persons or animals.
No Observable Adverse Effect Level. An exposure level at which there are no statistically or biologically significant increases in the frequency or severity of adverse effects between the exposed population and its appropriate control; some effects may be produced at this level, but they are not considered as adverse, or as precurors to adverse effects. In an experiment with several NOAELs, the regulatory focus is primarily on the highest one, leading to the common usage of the term NOAEL as the highest exposure without adverse effects.