Drugs that decrease the amount of testosterone produced by a man’s body. See “Hormonal Therapy” above.

man-made hormones, chemically similar to LHRH. They block the production of the male hormone testosterone and are sometimes used as a treatment for prostate cancer.

Synthetic compounds that are chemically similar to Luteinizing Hormone Releasing Hormone ( LHRH), but are sufficiently different that they suppress testicular production of testosterone by binding to the LHRH receptor in the pituitary gland and either have no biological activity and therefore competitively inhibit the action of LHRH, or has LHRH activity that exhausts the production of LH by the pituitary; used in the hormonal treatment of advanced prostate cancer and in the adjuvant  and neoadjuvant hormonal treatment of earlier stages of  prostate cancer; LHRH agonist (mimics natural LHRH but then shuts down LH production after continuous exposure)

Man-made compounds that are similar to, but more potent than, natural LHRH.