one of the five major classes of immunoglobulins; the main antibody defense against bacteria
an antibody containing substance produced by human plasma cells in diseased central nervous system plaques. Levels of IgG are increased in the cerebrospinal fluid of most MS patients.
the most common type of antibody in the plasma. IgG provides specific immunity against particular antigens, and is a major defense against bacteria, viruses and toxins. IgG initiates the complement cascade that result in the destruction of the membrane of pathogens. IgG extracted from donor plasma (gamma globulin) is used for passive immunization.
Immunoglobulin type gamma, the most common type found in the blood and tissue fluids.
The class of immunoglobulin normally present in largest amount in the blood. IgG can enter tissue space. It functions mainly against bacteria and some viruses by coating them, which speeds their uptake by other cells in the immune system.
The dominant class of antibodies and the one that provides long-term protection against infection. In pregnancy, IgG crosses the placenta to the fetus and protects it against infection. Also called gammaglobulin.
IgG is a monomeric immunoglobulin, built of two heavy chains γ and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans.
