giant papillary conjunctivitis. inflammation of the conjunctiva, most commonly associated with soft contact lens wear and marked by the presence of giant bumps or papillae (greater than 1 millimeter in diameter) on the posterior surface of the upper eyelids, as well as redness, itching, burning, mucous discharge, and blurred vision; may be related to irritation due to excess protein build-up on the lenses and/or to chemicals (such as preservatives) in the cleaning and sterilization solutions used to care for the lenses; treatment consists of decreasing (or even ceasing) contact lens wear, more frequent enzymatic cleaning of lenses (to remove protein deposits), discontinuance of preserved solutions, storage in unpreserved saline solutions, sterilization by hydrogen peroxide, and possibly obtaining new contact lenses
Giant papillary conjunctivitis (GPC) presents as multiple large, white bumps on the inside of the upper eyelids. These bumps then rub against the upper edge of the contact lens, causing significant irritation