A measure of the long-term control of blood glucose determined by the amount of carbohydrate-modified hemoglobin in the red blood cells. The higher the amount of glycosylated hemoglobin, the worse the control of blood glucose levels.
(HbA1c) is a measure of your average blood glucose level over the past several weeks.
A test that gives information about blood-glucose levels during the preceding 1-2 months. When blood glucose is above normal, the glucose changes the hemoglobin in red blood cells. These cells last for about 100 days, and they can be measured.
Hemoglobin molecules with glucose attached. Hemoglobin is a key molecule in red blood cells. No matter what a person's blood glucose level, a small proportion of hemoglobin molecules pick up glucose and become glycosylated. In people without diabetes, about 5% of hemoglobin is glycosylated. But as blood glucose levels rise, so does glycosylated hemoglobin. In people with poorly controlled diabetes, it can rise as high as 13%. A simple blood test, called the HbA1c test, reveals glycosylated hemoglobin level. It provides a snapshot of blood-glucose control during the previous two to three months.
2-3 month average of blood sugar values. Normal range varies from 4% - 6% depending on the individual laboratory. This table describes how HbA1c relates to blood sugar values. HbA1c Average Blood Sugar 10 60mg/dL 90mg/dL 120mg/dL 150mg/dL 180mg/dL 210mg/dL 240mg/dL
This measures the average glycemic control over approximately four months.
The iron-containing red pigment of red blood cells (hemoglobin) combined with a glucose derivative. When glucose is elevated, more glycosylate product is formed in the cells. Measurement of this hemoglobin reflects the blood glucose level over the previous several weeks; thus, it is a good indicator of blood glucose control in diabetics.
A widely used test item for the diagnosis and screening of diabetes and controlling blood sugar. This item reflects average blood-sugar levels over the past one or two months.
When blood glucose levels are high, excess glucose binds to hemoglobin fractions. This is used as an index of glucose control over time.
Glycosylated (or glycated) hemoglobin (hemoglobin A1c, Hb1c , HbA1c or HgA1c) is a form of hemoglobin used primarily to identify the plasma glucose concentration over time. Its name is sometimes abbreviated to A1C. It is formed in a non-enzymatic pathway by hemoglobin's normal exposure to high plasma levels of glucose.