Definitions for "Glucuronidation"
one of the major conjugation phase II reactions in the conversion of exogenous and endogenous compounds to polar, water-soluble compounds; facilitates excretion of toxic compounds from the body.
Glucuronidation is the process of chemically binding a substance to glucuronic acid via a glycosidic bond. The resulting glucuronide is typically much more water soluble than the original substance. The human body uses glucuronidation to excrete a large variety of molecules, including drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids and bile acids.