A laboratory test that determines how many copies of a specific segment of DNA are present or absent in a cell.
Fluorescent in situ hybridization (FISH) is a laboratory technique that uses fluorescently-labelled pieces of DNA to detect specific genes, chromosome segments or chromosomes, in cells examined under a special microscope.
(synonym: FISH) A technique used to identify the presence of specific chromosomes or chromosomal regions through hybridization (attachment) of fluorescently-labeled DNA probes to denatured chromosomal DNA. Examination under fluorescent lighting detects the presence of the hybridized fluorescent signal (and hence presence of the chromosome material) or absence of the hybridized fluorescent signal (and hence absence of the chromosome material).
A method of visualizing chromosomes that can allow scientists to look for gross chromosomal abnormalities.
a laboratory technique used to determine how many copies of a specific segment of DNA are present or absent in a cell.
Use of a single stranded DNA sequence with a fluorescent label to hybridize with its complementary target sequence in the chromosomes, allowing it to be visualized under ultraviolet light.
FISH (Fluorescent in situ hybridization) is a cytogenetic technique which can be used to detect and localize the presence or absence of specific DNA sequences on chromosomes. It uses fluorescent probes which bind only to those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosome.