Epidermal growth factor receptor (EGFR) is the receptor for epidermal growth factor (EGF). It is a member of the Erb B family receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.