a scientific study to determine the relationship between dose and response, and how much dose is correlated with how much response
estimates the probable human response to a substance in the concentration range to which humans are likely to be exposed.
The determination of the relationship between the magnitude of exposure (dose) to a chemical, biological or physical agent and the severity and/or frequency of associated adverse health effects (response).
A determination of the relationship between the magnitude of an administered, applied, or internal dose and a specific biological response. Response can be expressed as measured or observed incidence or change in level of response, percent response in groups of subjects (or populations), or the probability of occurrence or change in level of response within a population.
A determination of the relationship between the magnitude of an administered, applied, or internal dose and a specific biological response. Response can be expressed as measured or observed incidence, percent response in groups of subjects (or populations), or as the probability of occurrence within a population. This definition archived 9/30/03
1. Estimating the potency of a chemical. 2. In exposure assessment, the process of determining the relationship between the dose of a stressor and a specific biological response. 3. Evaluating the quantitative relationship between dose and toxicological responses.