Recently developed diagnostic tool based on the application of modern molecular genetics. In the future, DNA probes may provide more accurate, and possibly noninvasive diagnosis of prostate cancer.
A specific sequence of single-stranded DNA used to seek out a complementary sequence of single-stranded DNA. Probes are usually labelled radioactively or chemically to make them easier to detect, thus revealing the location of a target DNA sequence.
a chemically synthesized, radioactively labeled segment of nucleic acid used to find a gene of interest by hydrogen-bonding to a complementary sequence
a small piece of DNA complementary to the target DNA sequence
a small piece of the DNA chain, manufactured in a laboratory and tagged with a radioactive marker
a strand of radioactive DNA made by a synthesizer
A piece of DNA, labelled either chemically or with radioactivity, used in the laboratory to detect a specific gene, gene mutation or DNA marker.[CW2
a small segment of DNA labeled with a visible marker used to detect the presence of a particular type of organism by selective hybridization to a known, specific DNA sequence in that organism..
A small single strand of DNA used to identify its complement. Oligonucleotides are the DNA probes used in DNA microarrays.
See Nucleic Acid Hybridization Test.
A laboratory tool which is a specific sequence of a single-stranded DNA used to determine the presence fo a complementary sequence in other single strands.
A molecule (usually a nucleic acid) that has been labeled with a radioactive isotope, dye, or enzyme and is used to locate a particular nucleotide sequence or gene on a DNA molecule.
A single-stranded piece of DNA that binds specifically to a complementary DNA sequence; the probe is labeled (e.g., with a fluorescent or radioactive tag) in order to detect its incorporation through hybridization with DNA in a sample.
a piece of a DNA molecule used in laboratory experiments to detect the presence of a complementary DNA molecule or gene.
Any biochemical used to identify or isolate a gene, a gene product, or a protein.
a piece of single-stranded DNA, typically labeled so that it can be detected (for example, a radioactive or fluorescent label can be used), which can single out and bind with (and only with) another specific piece of DNA. DNA probes can be used to determine which sequences are present in a given length of DNA or which genes are present in a sample of DNA.
A chemically synthesized, often radioactively labeled, segment of DNA used to visualize a genomic sequence of interest by hydrogen-bonding to its complementary sequence.
A segment of DNA specifically designed to be complementary to a target sequence of chromosomes, genes or gene sequences. For FISH, the synthetic piece of DNA is coupled with a fluorescent indicator, or tag, so that the chromosomes or genes it binds (or hybridizes) to can be directly visualized.
a fragment of DNA used to recognize a specific complementary DNA sequence, or gene(s). Probes can be employed, for example, to bind to the genetic material of microbes for purposes of detection, identification, or, in some cases, inactivation.