12,13-epoxy-3,7,15-trihydroxytrichothec-9-en-8-one, one of a large family of sesquiterpene epoxide toxins known as trichothecenes.

Deoxynivalenol (DON, vomitoxin) is a type B trichothecene, an epoxy-sesquiter-penoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less often in rice, sorghum, and triticale. The occurrence of deoxynivalenol is associated primarily with Fusarium graminearum (Gibberella zeae) and F. culmorum, both of which are important plant pathogens which cause Fusarium head blight in wheat and Gibberella ear rot in maize.