Hyperactivity of the adrenal cortex, representing the most common endocrine disorder of horses.

A syndrome resulting from excess cortisone due to adrenal or pituitary dysfunction or excess medication. Cushing's disease is characterized by changes in body fat distribution ("moon face", "buffalo hump"), muscular weakness, metabolic disturbances and hirsutism (excess hair). A medical condition whereby electrolysis treatment is used as an adjunct therapy.

Condition due to tumors of the adrenal cortex or the anterior lobe of the pituitary gland. More common in women. Symptoms include fatness of the face, neck and trunk, softening of the spine, absence of menstruation, dusky complexion with purple markings, hypertension, muscular weakness and other serious symptoms. See Hypertension.