Definitions for "CREB"
A gene involved in learning and memory. It appears to be the master switch that activates a number of growth factors and potentially some anti-apoptotic genes. Recent studies suggest CREB is neuroprotective.
yclic-AMP esponse lement inding protein. CREB is a member of the basic region leucine zipper (bZIP) family of transcription factors and requires phosphorylation to become a biologically active transcriptional activator. CREB binds to CRE ( AMP esponse lement) which is the final target of many extracellular and intracellular signals (e.g. cAMP, calcium, neurotrophins). (More? Molecular Development)
A transcription factor.