CML is a disorder where too many granulocytes or myeloid cells, a type of white blood cell, are produced. This disease results in the abnormal accumulation of these cells in the marrow and the bloodstream and often the spleen. CML may occur at any age in either sex. It is uncommon before 10 years of age, and occurs at an average age of 45.
a slowly progressing cancer of the blood in which too many white blood cells are produced in the bone marrow.
Leukemia of the granulocytes. Starts with cells that still mature normally. After a certain period of time may transform into a more acute leukemia (blast crisis), frequently via a transition ("accelerated") phase
The Condition"About 4,400 new cases of chronic myelogenous leukemia (CML) are diagnosed each year in the United States..."
(also called CML or chronic granulocytic leukemia) - A disease in which too many white blood cells are made in the bone marrow. Chronic leukemia progresses more slowly than the acute form and has more mature-looking cancer cells.
(KRAH-nik my-ah-LAH-jeh-ness loo-KEE-mee-ah) Cancer of the blood system in which too many white blood cells are made in the bone marrow. Also called chronic myeloid leukemia or chronic granulocytic leukemia. Click here for more information about chronic myelogenous leukemia.
A slowly progressing disease usually associated with a chromosomal abnormality called the Philadelphia chromosome. Chronic myelogenous leukemia is characterized by increased production of a type of white blood cell called granulocytes in the bone marrow.
The Condition"...Unlike acute myelogenous leukemia (AML), chronic myelogenous leukemia permits the development of mature white blood cells that generally can function normally..."
A slowly progressing condition marked by the proliferation of abnormal white blood cells called granulocytes; leaves the body susceptible to anemia, infection, and bleeding.
long term over-production of immature blood cells.
A chronic malignant disease in which too many white blood cells belonging to the myeloid line of cells are made in the bone marrow . Early symptoms of this form of leukemia include fatigue and night sweats . The disease is due to the growth and evolution of an abnormal clone of cells containing a chromosome rearrangement known as the Philadelphia (or Ph) chromosome. Chronic myelogenous leukemia is commonly called CML. It is also known as chronic myelocytic leukemia and chronic granulocytic leukemia. See the entire definition of Chronic myelogenous leukemia
Myelogenous leukemia marked by an increase in immature and mature white blood cells. Has a slower progression than acute leukemia.
A disease that progresses slowly and is characterized by increased production of granulocytes in the bone marrow. It is usually associated with a specific chromosomal abnormality called the Philadelphia chromosome.
type of blood cancer that involves accumulation of granulocytes (a type of white blood cells) in the bone marrow and bloodstream.
CML. A slowly progressing disease in which too many white blood cells (not lymphocytes) are made in the bone marrow. Also called chronic myeloid leukemia or chronic granulocytic leukemia.
A chronic leukemia affecting the myeloid cell line. Usually affects people in their 50's or 60's but may occur in infants. If a Philadelphia chromosome abnormality is present on cells 60-70 % will progress to an acute phase.
A type of leukemia in which too many white blood cells grow in the bone marrow. Learn more.
Abnormal maturation and proliferation of white blood cell precursors of myeloid tissue. Characterized by abnormal proliferation of mature leukocytes (white blood cells). A disease similar to acute myelogenous leukemia except that it is a slowly progressive disease. It is rare in children and more common in adults.
A cancer of the myelocytes on the white blood cells. CML can happen at any age in either males or females. It is rare before age 10 and occurs most often in persons over age 45.
The Condition"...This change in the stem cell's DNA confers a growth and survival advantage on the malignant stem cell..."
Chronic myelogenous leukemia (CML) is a form of chronic leukemia characterized by increased and unregulated clonal production of predominantly myeloid cells in the bone marrow. CML is a myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome. Historically, it has been treated with chemotherapy, interferon and bone marrow transplantation, although targeted therapies introduced at the beginning of the 21st century have radically changed the management of CML.