Definitions for "ACE inhibitors"
Angiotensin-converting enzyme inhibitors, used to treat hypertension.
ACE inhibitors work by helping to stop the body from reacting to certain hormones that cause negative effects on the heart and blood flow. ACE inhibitors are considered "vasodilators," because they dilate, or widen, blood vessels.
ACE inhibitors are commonly used to lower blood pressure. They do this by blocking the action of an enzyme (ACE) that converts the inactive hormone angiotensin I to the active hormone angiotensin II and is also responsible for the degradation of bradykinin. The absence of angiotensin II and increased levels of bradykinin results in a widening of the arteries, thereby causing a fall in blood pressure.
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